In May 2014, the U.S. Department of Health and Human services (HHS) updated the HHS Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents (HHS treatment guidelines). The recommended frequency of CD4 count monitoring changed, reflecting the continuing evolution of HIV care. The CD4 count test remains the most important indicator of immune function. However, for patients with sustained virologic control and adequate immunologic recovery, the CD4 count test provides limited information and rarely leads to a change in clinical management; therefore, many patients who are stable and doing well on treatement may need less frequent CD4 testing or none at all.
Click the following link to read the updated Guidelines at AIDSinfo — Updated HHS Guidelines on CD4 Monitoring
Here is a signed letter from Dr. Laura Cheever, providing information about the revised recommendations as well as related information for reporting and clinical quality management programs.